Scopoletin belongs to a group of compounds called coumarins. In a variety of scientific studies scopoletin has been described variously as having hepatoprotective activity (cares for the liver), inhibiting the growth of Escherichia coli in the gut and antibacterial against Staphylococcus aureus, Strep. pneumoniae, Streptococcus sp., Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa and Haemophilus
influenzae. These various species of bacteria are responsible for such disorders as food poisoning, septicemia, pneumonia, nephritis, urogenital infections, endocarditis, respiratory infections, gastroenteritis and many more.

In addition scopoletin has shown a strong anti-inflammatory effect that has been particularly useful in the treatment of bronchial illnesses and asthma , in fact, it has been shown to be five times more effective than aspirin. Other studies have shown scopoletin to be useful as a topical application , antipyretic (fever reducing), analgesic, bacteriostatic, , antifungal and hypotensive hypotensive (lowers blood pressure). It is of interest that studies have shown when scopoletin is ingested in large amounts in foods in which it naturally occurs (other than Noni), that blood pressure can be driven down to hypotensive (ie. lower than desireable) levels. However, reports of the lowering of blood pressure in individuals drinking Noni juice have not found this same effect. Blood pressure, when it does lower from abnormally high levels in individuals drinking Noni juice, comes to rest at normal levels. There appears to be some control factor within the Noni juice that prevents the abnormally low blood pressure effects of scopoletin.
Synergy at work again.